\u0130\u00e7 Hastal\u0131klar\u0131 Uzman\u0131 Dr. Burak Uzel, t\u0131p d\u00fcnyas\u0131nda b\u00fcy\u00fck yank\u0131 uyand\u0131ran ve kanser geli\u015fimini hen\u00fcz h\u00fccresel a\u015famadayken durdurmay\u0131 hedefleyen NOUS-209 adl\u0131 \u201ckanser \u00f6nleme a\u015f\u0131s\u0131\u201dna ili\u015fkin geli\u015fmeleri a\u00e7\u0131klad\u0131. Genetik olarak kansere yatk\u0131n bireyler i\u00e7in umut vadeden bu \u00e7al\u0131\u015fma, onkoloji alan\u0131nda \u00e7\u0131\u011f\u0131r a\u00e7\u0131c\u0131 bir ad\u0131m olarak de\u011ferlendiriliyor.<\/p>\n
Geleneksel a\u015f\u0131lar\u0131n aksine viral enfeksiyonlar\u0131 de\u011fil, do\u011frudan kanserle\u015fme s\u00fcrecini hedef alan NOUS-209\u2019un, genetik mutasyonlara ba\u011fl\u0131 geli\u015fen kanserleri \u00f6nlemeyi ama\u00e7layan ilk a\u015f\u0131 adaylar\u0131ndan biri oldu\u011fu belirtildi. Dr. Uzel, bu yakla\u015f\u0131m\u0131n t\u0131p tarihinde bir d\u00f6n\u00fcm noktas\u0131 niteli\u011fi ta\u015f\u0131d\u0131\u011f\u0131na dikkat \u00e7ekti.<\/p>\n
Bug\u00fcne kadar kanserle ili\u015fkili a\u015f\u0131lar\u0131n \u00e7o\u011funun HPV veya Hepatit B gibi vir\u00fcs kaynakl\u0131 hastal\u0131klar\u0131 engellemeye y\u00f6nelik oldu\u011funa i\u015faret eden Uzel, NOUS-209\u2019un ise genetik yatk\u0131nl\u0131\u011f\u0131 olan bireylerde kansere giden s\u00fcreci do\u011frudan bloke etmeyi hedefledi\u011fini ifade etti. Dr. Uzel, \u201c\u0130lk kez v\u00fccudun kendi h\u00fccrelerindeki genetik bozulmalara ba\u011fl\u0131 geli\u015fen kanserle\u015fme s\u00fcrecine kar\u015f\u0131 bir ba\u011f\u0131\u015f\u0131kl\u0131k yan\u0131t\u0131 olu\u015fturulmas\u0131 ama\u00e7lan\u0131yor. Gelecekte bu t\u00fcr a\u015f\u0131lar\u0131n, grip a\u015f\u0131lar\u0131 gibi yayg\u0131n \u015fekilde uygulanabildi\u011fi bir sa\u011fl\u0131k sistemine do\u011fru ilerliyoruz\u201d dedi.<\/p>\n<\/p>\n
\u00c7al\u0131\u015fmalar\u0131n \u00f6zellikle Lynch Sendromu \u00fczerinde yo\u011funla\u015ft\u0131\u011f\u0131 bildirildi. Lynch Sendromu, bireyleri ba\u015fta kal\u0131n ba\u011f\u0131rsak ve rahim kanseri olmak \u00fczere bir\u00e7ok kanser t\u00fcr\u00fcne kar\u015f\u0131 y\u00fcksek risk alt\u0131na sokan kal\u0131tsal bir genetik hastal\u0131k olarak biliniyor.<\/p>\n
Klinik \u00e7al\u0131\u015fmalara ili\u015fkin payla\u015f\u0131lan bilgilere g\u00f6re; a\u015f\u0131, kanserli h\u00fccrelerde g\u00f6r\u00fclen de\u011fi\u015fimleri taklit eden yakla\u015f\u0131k 209 farkl\u0131 antijen i\u00e7eriyor. \u0130ki ay arayla uygulanan iki dozdan olu\u015fan a\u015f\u0131 takviminin, \u201cmikrosatellit instabilitesi\u201d (MSI) bulunan h\u00fccreleri kanserle\u015fme ba\u015flamadan yok etmeyi hedefledi\u011fi aktar\u0131ld\u0131. Bu y\u00f6n\u00fcyle NOUS-209\u2019un, kanseri tedavi etmekten ziyade ortaya \u00e7\u0131kmas\u0131n\u0131 \u00f6nlemeyi ama\u00e7layan proaktif bir yakla\u015f\u0131m sundu\u011fu vurguland\u0131.<\/p>\n
Erken te\u015fhisin \u00f6tesinde \u201cbirincil koruma\u201d kavram\u0131n\u0131n \u00f6nemine dikkat \u00e7eken Dr. Burak Uzel, ailesinde \u00f6zellikle gen\u00e7 ya\u015fta kal\u0131n ba\u011f\u0131rsak ya da rahim kanseri \u00f6yk\u00fcs\u00fc bulunan bireylerin Lynch Sendromu konusunda bilin\u00e7lenmesi gerekti\u011fini ifade etti.<\/p>\n
Atak\u00f6y Medicana Hastanesi\u2019nde \u0130\u00e7 Hastal\u0131klar\u0131 Uzman\u0131 olarak g\u00f6rev yapan Dr. Burak Uzel, ayn\u0131 zamanda dijital patoloji ve yapay zeka alan\u0131nda \u00e7al\u0131\u015fmalar y\u00fcr\u00fcten Virasoft\u2019un Bilim Direkt\u00f6r\u00fc (CSO) olarak da g\u00f6rev al\u0131yor. Dr. Uzel, t\u0131bbi alandaki g\u00fcncel geli\u015fmeleri dijital platformlar arac\u0131l\u0131\u011f\u0131yla payla\u015farak toplumda sa\u011fl\u0131k fark\u0131ndal\u0131\u011f\u0131n\u0131 art\u0131rmay\u0131 ama\u00e7l\u0131yor.<\/p>\n
<\/strong> \u0130stanbul, 23 Ocak (Hibya) – \u0130\u00e7 Hastal\u0131klar\u0131 Uzman\u0131 Dr. Burak Uzel, t\u0131p d\u00fcnyas\u0131nda b\u00fcy\u00fck yank\u0131 uyand\u0131ran ve kanser geli\u015fimini hen\u00fcz h\u00fccresel a\u015famadayken durdurmay\u0131 hedefleyen NOUS-209 adl\u0131 \u201ckanser \u00f6nleme a\u015f\u0131s\u0131\u201dna ili\u015fkin geli\u015fmeleri payla\u015ft\u0131.<\/p>\n","protected":false},"author":1,"featured_media":37257,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"googlesitekit_rrm_CAow07ekDA:productID":"","footnotes":""},"categories":[4],"tags":[],"class_list":["post-37256","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-dunya"],"_links":{"self":[{"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/37256","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/comments?post=37256"}],"version-history":[{"count":0,"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/37256\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/media\/37257"}],"wp:attachment":[{"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/media?parent=37256"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/categories?post=37256"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/tags?post=37256"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\nEKONOM\u0130 GAZETES\u0130 <\/p>\n","protected":false},"excerpt":{"rendered":"