Medicana Atak\u00f6y Hastanesi \u0130\u00e7 Hastal\u0131klar\u0131 Uzman\u0131 Dr. Burak Uzel, Tip 2 diyabet hastalar\u0131nda kolesterol d\u00fc\u015f\u00fcr\u00fcc\u00fc statin ila\u00e7lar\u0131n\u0131n kullan\u0131m zaman\u0131 ile demans riski aras\u0131ndaki ili\u015fkiye dikkat \u00e7ekti.<\/p>\n
The Lancet Regional Health \u2013 Europe dergisinde yay\u0131mlanan bir ara\u015ft\u0131rmada, Tip 2 diyabet tan\u0131s\u0131 alan ki\u015filerde statin tedavisine ba\u015flama zaman\u0131 ile demans geli\u015fme riski aras\u0131ndaki ili\u015fki incelendi. Yakla\u015f\u0131k 130 bin ki\u015finin verilerine dayanan \u00e7al\u0131\u015fmada, diyabet tan\u0131s\u0131ndan sonraki ilk y\u0131l i\u00e7inde statin tedavisine ba\u015flayanlarda demans riskinin daha d\u00fc\u015f\u00fck oldu\u011fu g\u00f6r\u00fcld\u00fc.<\/p>\n
Ara\u015ft\u0131rman\u0131n 10 y\u0131ll\u0131k risk hesaplamalar\u0131na g\u00f6re, statin kullanmayanlarda demans riski y\u00fczde 3,9 olarak belirlenirken, diyabet tan\u0131s\u0131ndan 1 ila 5 y\u0131l sonra tedaviye ba\u015flayanlarda bu oran y\u00fczde 3,5, ilk y\u0131l i\u00e7inde ba\u015flayanlarda ise y\u00fczde 3,3 olarak hesapland\u0131. Bu sonu\u00e7lar, erken statin kullan\u0131m\u0131 ile daha d\u00fc\u015f\u00fck demans riski aras\u0131nda ili\u015fki bulundu\u011funu ortaya koydu. Ancak ara\u015ft\u0131rma g\u00f6zlemsel nitelik ta\u015f\u0131d\u0131\u011f\u0131 i\u00e7in sonu\u00e7lar, statin tedavisinin demans\u0131 do\u011frudan \u00f6nledi\u011fini tek ba\u015f\u0131na kan\u0131tlam\u0131yor.<\/p>\n
Damar kaynakl\u0131 demans riski de incelendi<\/p>\n
Ara\u015ft\u0131rmada damar kaynakl\u0131 demans sonu\u00e7lar\u0131 da de\u011ferlendirildi. Bu grupta 10 y\u0131ll\u0131k risk, statin kullanmayanlarda y\u00fczde 2,9, tedaviye diyabet tan\u0131s\u0131ndan sonraki ilk y\u0131l i\u00e7inde ba\u015flayanlarda ise y\u00fczde 2,3 olarak hesapland\u0131.<\/p>\n<\/p>\n
Medicana Atak\u00f6y Hastanesi \u0130\u00e7 Hastal\u0131klar\u0131 Uzman\u0131 Dr. Burak Uzel, bulgular\u0131 de\u011ferlendirirken damar sa\u011fl\u0131\u011f\u0131 ile beyin sa\u011fl\u0131\u011f\u0131 aras\u0131ndaki ili\u015fkiye dikkat \u00e7ekti. Uzel, y\u00fcksek kolesterol\u00fcn ve damar hasar\u0131n\u0131n kontrol alt\u0131nda tutulmas\u0131n\u0131n uzun vadeli sa\u011fl\u0131k a\u00e7\u0131s\u0131ndan \u00f6nem ta\u015f\u0131d\u0131\u011f\u0131n\u0131 belirtti.<\/p>\n
Kad\u0131n ve erkek hastalar aras\u0131ndaki farklar<\/p>\n
Ara\u015ft\u0131rmada kad\u0131nlar\u0131n 10 y\u0131ll\u0131k demans riski y\u00fczde 4,9, erkeklerin riski ise y\u00fczde 3,1 olarak hesapland\u0131. Erken d\u00f6nemde statin tedavisine ba\u015flayan grubun y\u00fczde 40,5\u2019ini kad\u0131nlar olu\u015fturdu.<\/p>\n
Uzel, kad\u0131n diyabet hastalar\u0131nda kolesterol tedavisinin ve LDL olarak bilinen k\u00f6t\u00fc kolesterol d\u00fczeylerinin hekim kontrol\u00fcnde takip edilmesinin \u00f6nemini vurgulad\u0131. Uzel, Tip 2 diyabet hastalar\u0131n\u0131n kolesterol tedavisi gereksinimlerini doktorlar\u0131yla de\u011ferlendirmesi gerekti\u011fini ifade etti.<\/p>\n
Tedavi karar\u0131 hekim taraf\u0131ndan verilmeli<\/p>\n
Statin ila\u00e7lar\u0131, kolesterol d\u00fczeyini d\u00fc\u015f\u00fcrmek ve kalp-damar hastal\u0131\u011f\u0131 riskini azaltmak amac\u0131yla kullan\u0131l\u0131yor. Uzel, Tip 2 diyabet hastalar\u0131n\u0131n doktorlar\u0131 taraf\u0131ndan \u00f6nerilen tedavileri kendi kararlar\u0131yla ertelememeleri veya de\u011fi\u015ftirmemeleri gerekti\u011fini belirtti.<\/p>\n
Ara\u015ft\u0131rman\u0131n sonu\u00e7lar\u0131, statin tedavisine ba\u015flama zaman\u0131 ile demans riski aras\u0131nda ili\u015fki bulundu\u011funa i\u015faret ediyor. \u0130lac\u0131n kullan\u0131m\u0131 ve tedaviye ba\u015flama zaman\u0131 ise ki\u015finin sa\u011fl\u0131k durumu ve risk fakt\u00f6rleri dikkate al\u0131narak hekim taraf\u0131ndan belirleniyor.<\/p>\n
Ara\u015ft\u0131rman\u0131n k\u00fcnyesi: Ternhamar T, Johansen M\u00d8, Nordestgaard BG, Afzal S. \u201cAssociation between timing of statin treatment after diabetes diagnosis and risk of dementia: a nationwide observational study.\u201d The Lancet Regional Health \u2013 Europe, 2026.<\/p>\n
<\/strong> \u0130stanbul, 20 Ekim (Hibya) – Medicana Atak\u00f6y Hastanesi \u0130\u00e7 Hastal\u0131klar\u0131 Uzman\u0131 Dr. Burak Uzel, Tip 2 diyabet hastalar\u0131nda kolesterol d\u00fc\u015f\u00fcr\u00fcc\u00fc statin ila\u00e7lar\u0131n\u0131n kullan\u0131m zaman\u0131 ile demans riski aras\u0131ndaki ili\u015fkiye dikkat \u00e7ekti.<\/p>\n","protected":false},"author":1,"featured_media":169835,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"googlesitekit_rrm_CAow07ekDA:productID":"","footnotes":""},"categories":[4],"tags":[],"class_list":["post-169834","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-dunya"],"_links":{"self":[{"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/169834","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/comments?post=169834"}],"version-history":[{"count":0,"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/169834\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/media\/169835"}],"wp:attachment":[{"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/media?parent=169834"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/categories?post=169834"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/tags?post=169834"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\nEKONOM\u0130 GAZETES\u0130 <\/p>\n","protected":false},"excerpt":{"rendered":"