\u0130\u00e7 Hastal\u0131klar\u0131 Uzman\u0131 Dr. Burak Uzel, aterosklerotik kardiyovask\u00fcler hastal\u0131k \u00f6yk\u00fcs\u00fc bulunan ki\u015filerde LDL kolesterol hedeflerine ili\u015fkin de\u011ferlendirmelerde bulundu.<\/p>\n
Uzel’in aktard\u0131\u011f\u0131 \u00e7al\u0131\u015fmada, LDL kolesterol seviyesinin daha d\u00fc\u015f\u00fck hedeflenmesinin kardiyovask\u00fcler sonu\u00e7lar \u00fczerindeki etkisi incelendi. Yakla\u015f\u0131k 3 bin hastan\u0131n 3 y\u0131l boyunca takip edildi\u011fi ara\u015ft\u0131rmada, kat\u0131l\u0131mc\u0131lar LDL kolesterol hedefi 70 mg\/dL’nin alt\u0131 ve 55 mg\/dL’nin alt\u0131 olacak \u015fekilde iki gruba ayr\u0131ld\u0131.<\/p>\n
\u00c7al\u0131\u015fma sonu\u00e7lar\u0131na g\u00f6re, LDL kolesterol hedefi 55 mg\/dL’nin alt\u0131nda olan grupta maj\u00f6r kardiyovask\u00fcler olay g\u00f6r\u00fclme oran\u0131 y\u00fczde 6,6 olurken, 70 mg\/dL’nin alt\u0131nda hedeflenen grupta bu oran y\u00fczde 9,7 olarak kaydedildi.<\/p>\n
Uzel, iki grup aras\u0131ndaki y\u00fczde 3,1’lik fark\u0131n, kardiyovask\u00fcler hastal\u0131k \u00f6yk\u00fcs\u00fc bulunan y\u00fcksek riskli ki\u015filer a\u00e7\u0131s\u0131ndan dikkate de\u011fer oldu\u011funu belirtti.<\/p>\n
\u00c7al\u0131\u015fmada ayr\u0131ca LDL kolesterol seviyesinin 55 mg\/dL’nin alt\u0131na d\u00fc\u015f\u00fcr\u00fcld\u00fc\u011f\u00fc grupta ciddi yan etki oran\u0131nda anlaml\u0131 bir art\u0131\u015f saptanmad\u0131\u011f\u0131 bildirildi.<\/p>\n
\n
Uzel, de\u011ferlendirmesinde kardiyovask\u00fcler hastal\u0131k \u00f6yk\u00fcs\u00fc bulunan ki\u015filerde LDL kolesterol hedeflerinin 70 mg\/dL’nin alt\u0131yla s\u0131n\u0131rl\u0131 tutulmamas\u0131 gerekti\u011fini ifade etti. Uzel, LDL hedefinin daha d\u00fc\u015f\u00fck belirlenmesinin kardiyovask\u00fcler olay riskinde azalmayla ili\u015fkili oldu\u011funu ve \u00e7al\u0131\u015fmada ciddi yan etki art\u0131\u015f\u0131 g\u00f6r\u00fclmemesinin tedavi a\u00e7\u0131s\u0131ndan \u00f6nem ta\u015f\u0131d\u0131\u011f\u0131n\u0131 kaydetti.<\/p>\n
S\u00f6z konusu de\u011ferlendirmeler, 2026 y\u0131l\u0131nda The New England Journal of Medicine dergisinde yay\u0131mlanan \u201cIntensive LDL Cholesterol Targeting in Atherosclerotic Cardiovascular Disease\u201d ba\u015fl\u0131kl\u0131 \u00e7al\u0131\u015fmaya dayan\u0131yor.<\/p>\n
<\/strong> \u0130stanbul, 24 A\u011fustos (Hibya) – \u0130\u00e7 Hastal\u0131klar\u0131 Uzman\u0131 Dr. Burak Uzel, aterosklerotik kardiyovask\u00fcler hastal\u0131k \u00f6yk\u00fcs\u00fc bulunan ki\u015filerde LDL kolesterol hedeflerine ili\u015fkin de\u011ferlendirmelerde bulundu.<\/p>\n","protected":false},"author":1,"featured_media":137269,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"googlesitekit_rrm_CAow07ekDA:productID":"","footnotes":""},"categories":[4],"tags":[],"class_list":["post-137268","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-dunya"],"_links":{"self":[{"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/137268","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/comments?post=137268"}],"version-history":[{"count":0,"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/137268\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/media\/137269"}],"wp:attachment":[{"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/media?parent=137268"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/categories?post=137268"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ekonomigundemi.com.tr\/index.php\/wp-json\/wp\/v2\/tags?post=137268"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\nEKONOM\u0130 GAZETES\u0130 <\/p>\n","protected":false},"excerpt":{"rendered":"